NeoPhe LNAA Lemon Flavored Powder

Flavored LNAA powder

A Medical Food for the dietary management of Phenylketonuria (PKU) and Hyperphenylalaninemia (HPA). Not for the general population of consumers or maternal PKU patients.

Product Label

Out of stock


Lower Blood Phe with NeoPhe.
When patients need to lower their blood Phe, they may do so effectively with Solace Nutrition’s NeoPhe Lemon-Flavored Powder. This medical food powder contains a clinically proven combination of large neutral amino acids (LNAA) that block Phenylalanine at the gut level, resulting in lower blood Phenylalanine.

Ideal for the potential support of Phenylketonuria (PKU) and Hyperphenylalaninemia (HPA), this soluble powder is available for purchase for those under medical supervision and current medical care. It is not meant for maternal PKU patients.

NeoPhe Lemon-Flavored Powder only contains ingredients that have been researched or scientifically backed for their benefits. It likewise only contains nutrients that have a daily requirement. Solace Nutrition’s NeoPhe is available in both powder and tablet form to suit your patients’ preference. Both are convenient and easy to use.

Clinically Proven

  • Data from pilot studies conducted in the Ukraine, Russia and the U.S. revealed a decrease in blood Phe concentration of 52% to 55% form baseline. When NeoPhe was discontinued, blood Phe concentrations increased to pre-trial levels.1
  • Double-blind studies performed in seven (7) different centers indicate that LNAA can compete with Phe on the transporter in the GI tract, resulting in a decrease in the blood Phe-level in patients on NeoPhe, averaging 39% from baseline levels.2


  • Adults, teenagers and children 8 years or older
  • BH4 non-responders
  • High blood Phe levels despite strong diet compliance
  • Non compliant, untreated or late-diagnosed PKU patients


  • Monitor blood Phe levels for tolerance.
  • NeoPhe tablets and powder can be used interchangeably.
  • NeoPhe results in liberalization of the diet for most PKU patients.
  • Decrease in consumption of low-protein foods.

1) R. Matalon, K.  Michals-Matalon, G. Bhatia, E. Grechanina, P. Novikov, D. J. McDonald, J. Grady, S.K. Tyring, F. Guttler, Large Neutral Amino Acids in the Treatment of Phenylketonuria (PKU), J Inherit Metab Dis. 2006 Dec;29(6):732-8. 
 R. Matalon, K. Michals-Matalon, G. Bhatia, A.B. Burlina, A.P. Burlina, C. Braga, L. Fiori, M. Giovannini, E. Grechanina, P. Novikov, J. Grady, S.K. Tyring,  F.Guttler, Double blind placebo control trial of large neutral amino acids in treatment of PKU: Effect on blood phenylalanine. J Inherit Metab Dis. 2007, Feb 27.

View Dietary Reference Intakes (DRI) Values


L-Tyrosine, Fructose, L-Leucine, L-Tryptophan, L-Isoleucine, L-Valine, L-Lysine , Artificial Lemon Flavoring, L-Threonine, L-Arginine, L-Histidine, L-Methionine, Sucrose Palmitate, Magnesium, Silica, Sucralose, Riboflavin, Vitamin B6, Folic Acid, Biotin, Vitamin B12.

Directions for Use

Suggested Intake: 0.5 g amino acids per kg of body weight per day (0.5 g amino acids/kg/d).

Daily intake to be determined by your healthcare professional specialized in metabolic disorders. The dosage is dependant on the age, body weight, medical condition and individual Phe tolerance. NeoPhe is not suitable as a sole source of nutrition.

NeoPhe must always be taken with food. NeoPhe must be supplemented with a moderately restricted PKU diet containing other sources of protein, vitamins and minerals. An individualized diet plan must be followed at all times.

Additional information

Weight 0.95 lbs
Dimensions 4 × 4 × 3.5 in


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