Description
PSACH Care™ is a medical food in softgel form designed for the dietary management of joint degeneration and discomfort associated with Pseudoachondroplasia (PSACH) and other skeletal dysplasias. It is intended for use under medical supervision as part of a comprehensive care plan.
Pseudoachondroplasia is a rare genetic skeletal dysplasia characterized by disproportionate short-limb stature, joint laxity, and early-onset osteoarthritis. Unlike more common forms of dwarfism, individuals with PSACH often experience more severe joint and cartilage degeneration beginning in early childhood, frequently leading to significant mobility challenges and early orthopedic intervention.
PSACH Care™ is formulated to address the underlying cellular and inflammatory processes that contribute to disease progression, with a focus on supporting joint health, reducing discomfort, and preserving cartilage integrity.
Benefit Summary
PSACH Care™ is designed to:
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Reduce joint pain and discomfort at all stages of PSACH
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Support improved limb growth when used in early stages of development
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Decrease malformed cartilage oligomeric matrix protein (COMP) buildup in cartilage cells
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Reduce joint inflammation
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Help prevent chondrocyte (cartilage cell) death
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Support preservation of cartilage volume over time
Mechanism of Action
PSACH is caused by an inborn genetic mutation leading to the accumulation of misfolded COMP protein within chondrocytes. This buildup creates cellular stress, triggers inflammation, and results in premature cartilage cell death.
PSACH Care™ contains CurQ+®, a highly bioavailable, coconut oil-based curcumin formulation designed to support multiple key pathways:
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Reduces intracellular accumulation of misfolded COMP protein
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Lowers joint inflammation
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Increases autophagy (cellular cleanup processes)
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Helps protect chondrocytes from stress-induced cell death
The anti-inflammatory properties of CurQ+® help address chronic joint pain and inflammation in children with PSACH—areas where long-term NSAID use may be limited due to safety concerns.
Who It’s For
PSACH Care™ is intended for individuals diagnosed with:
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Pseudoachondroplasia (PSACH)
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Other skeletal dysplasias associated with joint degeneration and inflammation
PSACH is typically diagnosed between ages 2–4, when growth slows and a waddling gait becomes apparent. It affects approximately 1 in 30,000–40,000 births and is associated with significant joint challenges throughout life.
Product Details
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Form: Softgel
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Active Ingredient: CurQ+® (curcumin-based formulation developed by Stratum Nutrition)
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Strength: 400 mg CurQ+® per softgel
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Curcuminoids: 65 mg per softgel
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Count: 30 softgels per bottle