| Home : Products : SLOesterol |
SLOesterol is a Medical Food specifically formulated using a proprietary microencapsulation process. SLOesterol represents a practical solution to the dosing of synthetic cholesterol for the SLOS patient.
SLOesterol contains a proprietary lipid micro-encapsulation process which offers the following advantages:
What is Smith-Lemli-Opitz Syndrome (SLOS)?
Smith-Lemli-Opitz Syndrome (SLOS) is a genetic disorder caused by a mutation that impairs or completely stops the last step of cholesterol production, leading to varying degrees of deficiency of cholesterol. The disease is homozygous recessive, meaning that a child needs to receive an abnormal gene from each parent. It is estimated that carriers of the gene may be as common as 1 in every 30 people with disease incidences on the order of 1 in 13,000 to 1 in 40,000. Some children with SLOS have no detectable cholesterol in their blood serum. Children or adults with SLOS have varying degrees of impairment that depend on the particular mutation in the gene that causes cholesterol deficiency of different degrees.
SLOS is a Metabolic Disorder caused by a mutation in the DHCR7 (7-dehydrocholesterol reductase) gene on chromosome 11
Reference Robert D Steiner, MD, Professor, Departments of Pediatrics and Molecular and Medical Genetics, Vice Chair for Research, Department of Pediatrics, Oregon Health & Science University; Director and Consulting Staff, Metabolic Bone Disease Clinic, Shriner's Hospital and Doernbecher Children's Hospital; Co-Director: Pediatric and Child Health Research, Oregon Clinical and Translational Research Institute (CTSA). http://emedicine.medscape.com/article/949125-overview
How is SLOS diagnosed?
SLOS is confirmed by measurement of cholesterol and 7-dehydrocholesterol (7-DHC) by gas-chromatography mass spectrometry of blood serum. The gene defect leads to low total cholesterol and elevated amounts of the cholesterol precursors 7-DHC and 8-DHC.
Why does a person with SLOS need cholesterol?
Cholesterol is a critical building block needed for all tissues and cells as a part of the cell membrane. Cholesterol is especially high in the peripheral nerves and in the spinal cord and brain. Myelin, the protective and insulating material that surrounds the nerve cells, is composed of cholesterol. Dysfunction in the myelin of nerve fibers causes the interruption of smooth delivery of neurological information.
Clinical Features of SLOS
Product Form
Indications
*Conversion: 1 level scoop = 1 g cholesterol
Ingredients: Cholesterol, Soy Oil, Vitamin C, Vitamin E
Warning: Only for individuals with medical conditions requiring additional Cholesterol due to a defect in cholesterol synthesis, such as SLOS. Not to be used by individuals less than one (1) year of age. SLOesterol does not suspend well in liquids and may cause feeding tubes to block. Consult with a dietitian before attempting to tube feed SLOesterol.
Storage: Unopened bottles should be kept in a cool, dry, dark environment. Reseal opened bottles, store in a refrigerator and use within 3 months
SLOesterol - 888-8-765223
*National Drug Codes (NDC) Format Codes: Products sold by Solace Nutrition are classified as Medical Foods by the US Food and Drug Administration (FDA). NDC format codes are product codes adjusted according to standard industry practice to meet the format requirements of pharmacy and health insurance computer systems.
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A tasteless, microencapsulated, powdered Medical Food for the dietary management of Smith-Lemli-Opitz Syndrome (SLOS). For individuals with sterol disorders who cannot obtain the recommended intake of cholesterol through regular diet. Not for the general population of consumers.
Contact Solace Nutrition© Solace Nutrition
Site maintained and optimized by RobiDigital